National Action Plan for Adverse Drug Event (ADE) Prevention; Office of Disease Prevention and Health Promotion (ODPHP)

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The ADE Action Plan addresses a defined group of ADEs that are considered to be common, clinically significant, preventable, and measurable; resulting from high-priority drug classes; and occurring largely in high-risk populations. Three key drug classes identified as initial targets for the ADE Action Plan include; Anticoagulants (primary ADE of concern: bleeding), Diabetes agents (primary ADE of concern: hypoglycemia), and Opioids (primary ADE of concern: accidental overdoses, oversedation, respiratory depression).